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KMID : 0378019950380090017
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New Medical Journal
1995 Volume.38 No. 9 p.17 ~ p.22
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Electrophysiological Stuides of Peripheral Nerve Dysfunction in Diabetic Patients
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Abstract
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Although peripheral neuropathy in diabetic patients can be easily recognized when fully developed, it frequently present a difficult diagnostic challenge in its early stages. The electro physiologic study, especially nerve conduction study(NCS) is one of the most objective and qualitative method for the evaluation of peripheral neuropathy. However, some patients have infrequently normal ranges of NCS result even though may have definite symptoms and signs of diabetic neuropathy. In this study, the terminal latency, the motor nerve conduction velocity over wrist-elbow segment, and the residual latency on median and ulnar nerves were measured in 20 diabetic patients with symptomatic peripheral polyneuropathy whose electrophysiological studies were normal, and were compared with 20 normal subjects. Residual latency was calculated by dividing the distance between the cathode and active electrode by motor NCV and subtracting the quotient from the motor terminal latency.
The results are as follows:
1. There is no significant difference in latency and velocity of median and ulnar nerve between diabetic patients and normal controls.
2. The mean residual latency of diabetic patients is significantly prolonged compared to the normal control(p<0.05).
In conclusion, the residual latency may be more sensitive and useful in confirming early or mild diabetic neuropathy and particularly attractive because it dose not require an additional stimulation of that nerve, preventing the patients from the additional discomfort resulted by that procedure.
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